Searchable abstracts of presentations at key conferences in endocrinology

ea0026p3 | Adrenal cortex | ECE2011

MicroRNAs as endogenous modulators of glucocorticoid receptor expression in the adrenal gland after ACTH stimulation test

Hill A , Issler O , Spyroglou A , Haramati S , Chen A , Beuschlein F

MicroRNAs (miRs) are a subset of small RNA molecules that regulate gene expression post-transcriptionally. Little is known about the expression and the role of miRs in the adrenal gland. Thus, we determined the miRs expression pattern under baseline conditions and 10, 30 and 60 min after ACTH stimulation test in mice adrenal glands using miRs microarray. The miRs expression profile of adrenals obtained from the array was bioinformatically analyzed to indentify miRs that putati...